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Auditory Training (n = 27)
Computer Games (n = 29)
Baseline
Post
Baseline
Post
Outcome Measureb
Mean
SD
Mean
SD
Mean
SD
Mean
SD
Fa
p-v alue
Effect Size
Global Cognition
−1.12
0.93
−0.87
0.98
−0.96
0.85
−0.95
0.94
2.96
0.09
0.25
DBL MMNc
0.35
0.99
0.46
0.81
0.44
0.88
0.38
0.89
0.60
0.44
0.18
DUR MMNc
0.34
0.92
0.28
0.73
0.19
1.02
0.34
0.85
0.89
0.35
-0.23
FREQ MMNc
0.32
1.00
0.45
1.10
0.43
0.99
0.10
1.02
4.83
0.03
0.46
FREQ Frequency Deviant, DUR Duration Deviant, DBL Frequency + Duration Double-Deviant
MATRICS Measurement and Treatment Research to Improve Cognition in Schizophrenia
a Repeated measures ANOVA, Treatment Group x Time interaction
b Cognitive measures were transformed to z- scores using normative data of healthy samples. Global Cognition is the average z- score across all measures from the MATRICS
c Group mean and standard deviation (SD) mismatch negativity (MMN) age-corrected z-scores for each deviant type averaged over the six fronto-central leads (F3, Fz, F4, C3, Cz, C4)
Statistically significant p -values are formatted in bold