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Table 4 Global Cognition and Mismatch Negativity (MMN) Amplitude z-scores for Participants With Schizophrenia Who Received Computerized Auditory Training and Participants Who Played Computer Games

From: Trait aspects of auditory mismatch negativity predict response to auditory training in individuals with early illness schizophrenia

  Auditory Training (n = 27) Computer Games (n = 29)
Baseline Post Baseline Post  
Outcome Measureb Mean SD Mean SD Mean SD Mean SD Fa p-value Effect Size
Global Cognition −1.12 0.93 −0.87 0.98 −0.96 0.85 −0.95 0.94 2.96 0.09 0.25
DBL MMNc 0.35 0.99 0.46 0.81 0.44 0.88 0.38 0.89 0.60 0.44 0.18
DUR MMNc 0.34 0.92 0.28 0.73 0.19 1.02 0.34 0.85 0.89 0.35 -0.23
FREQ MMNc 0.32 1.00 0.45 1.10 0.43 0.99 0.10 1.02 4.83 0.03 0.46
  1. FREQ Frequency Deviant, DUR Duration Deviant, DBL Frequency + Duration Double-Deviant
  2. MATRICS Measurement and Treatment Research to Improve Cognition in Schizophrenia
  3. a Repeated measures ANOVA, Treatment Group x Time interaction
  4. b Cognitive measures were transformed to z-scores using normative data of healthy samples. Global Cognition is the average z-score across all measures from the MATRICS
  5. c Group mean and standard deviation (SD) mismatch negativity (MMN) age-corrected z-scores for each deviant type averaged over the six fronto-central leads (F3, Fz, F4, C3, Cz, C4)
  6. Statistically significant p-values are formatted in bold